August 25, 2026

In this episode of No Magic Pill, Blake Mycoskie sits down with Aubrey Marcus, founder of Onnit and one of the most respected voices in peak performance, consciousness, and plant medicine. Aubrey has built his entire life around one question: what does it actually mean to be fully human? He has gone deeper than most people are willing to go, and he is willing to talk about where it has gone right and where it has gone wrong.
Four weeks into fatherhood and fresh off finishing a book seven years in the making, Aubrey opens up about the first medicine journey that turned a staunch atheist into one of the most spiritually curious people Blake has ever met, the six days he spent in absolute darkness, and why the most important realization of his life is also the simplest: nobody else will ever be you. If you have ever felt the pull toward something bigger than yourself and did not know where to start, this conversation is your invitation.
Aubrey is four weeks into life as a dad, and the man who fades every hype admits the hype was right this time. The moment his daughter was born, something clicked on, a latent code that reordered everything at once: how is the kingdom, how is the world, how is my daughter, how is my wife. It was clarifying and wildly heart opening. He and Blake talk about what it means to have real skin in the game on the future, not just talking about caring for humanity but making a bet on it, working to build a future worthy of his daughter and raising her to be one of the changemakers of the next generation.
Asked to define the phrase Onnit was built on, Aubrey starts by dismantling the idea that mind, body, and spirit are separate. The body is the easiest place to work, and it produces far more of our thoughts, hormones, and energy than we realize, so the foundation comes first, then the practices, then connection to something bigger than yourself. That connection arrived for Aubrey in an unlikely way. A staunch atheist reading Christopher Hitchens, he sat with a shaman in Santa Fe for a journey combining MDMA and psilocybin, and everything opened. He beheld himself as part of an interconnected web of life, recognized a part of himself that is unborn and undying, and walked through visions of wheat fields he had never seen. Blake connects it to his own dark years of depression, when disconnection was the disease and connection turned out to be the antidote.
The two trade the non-psychedelic tools they reach for in a funk. Aubrey’s first advice comes from Zen master Shinzen Young: smile, and see how far it spreads. Then comes ecstatic dance, done sober, which frees the shackles of self-judgment until sound and movement merge into what psychologists call superfluidity. Blake shares his own love of dancing sober at Burning Man, and a TOMS-era memory of a laughter yoga coach who put chicken noses on 80 employees until the fake laughter turned real and his core ached like a gym day. Underneath all of it sits one principle Aubrey returns to: when you are in a funk, do not fixate on the destination. Just find the next best step.
With more than 500 podcast episodes behind him, Aubrey names the guests who left him a different person. A rabbi mentor taught him that we are each a unique configuration of desires, that the ego does not have to disappear, only transfigure into the unique self nobody else will ever be. A mystic Catholic priest, Father Sean Wheeler, wrecked him with the story of the soul who looks down at the earth, hears God ask who will go, and raises a hand: purpose with a capital P, liberation for all people, not just yourself. And the late Robert Gilbert introduced him to the idea of Ahriman, the reducer, the force that shrinks people down to what they are worth. Blake recognizes it instantly: his whole life was driven by a wound of not feeling enough, of being loved only if he performed, and the liberation came from finally knowing in his body that he is enough.
For anyone feeling stuck and curious, Aubrey lays out the honest path. Psychedelics are a 404-level class, and you do not skip the 101: understand your own psychology, take care of your body and mind, layer in meditation, breathwork, and flotation, and get comfortable with discomfort, because these journeys can be bliss or grueling white-knuckle rides. Then research which medicine you are called to, and always work with a guide who can lean over and remind you that what you are experiencing is normal. They compare notes on MDMA in ceremony versus recreation, and go deep on Huachuma, commonly known as San Pedro, the grandfatherly medicine of the Chavin lineage that is so powerful it can be gentle. Blake shares how a single light ceremony with it opened the core wound years of therapy had not reached, and both agree the integration afterward matters more than the experience itself.
Aubrey describes his six days in absolute pitch blackness near the Black Forest in Germany: two days of the mind trying to fix inside problems with outside solutions, then a flood of visions from day three on, and finally the moment he stepped out, lifted the blindfold to a sunset, water droplets, and an orange tabby cat, and sobbed at how much beauty had been around him all along. From there the conversation turns practical. Not making a choice is a choice, and Onnit itself was built on two failed supplements that became stepping stones to the right one. They swap morning routines built on hydration, light, and stillness, and Aubrey shares Marcus Luttrell’s line-in-the-sand story as the model for breaking impossible journeys into one next step. The closing message is the one Blake wants every listener to hear: your ancestors survived everything to bring you here, the help is already reaching toward you, and all you have to do is meet it halfway.
Aubrey Marcus is the founder of Onnit, a health and fitness company built around the idea of total human optimization, and the author of the bestselling book Own the Day, Own Your Life. Host of a podcast with more than 500 episodes and producer of a documentary exploring plant-based medicines, he has spent nearly three decades exploring peak performance, consciousness, and what it means to be a human being. He recently completed his next book, a companion to Own the Day for the mind and spirit, arriving in February.
Links
Instagram: @aubreymarcus
Website: https://www.aubreymarcus.com/
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MOOVLAB
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Follow Blake on Instagram at @blakemycoskie.
This episode is for informational and entertainment purposes only and is not intended as medical advice. Always consult a qualified healthcare professional with any medical questions or concerns.